A zestril prinivil lisinopril is an ace angiotensin converting enzyme inhibitor, used to treat hypertension, chf congestive heart failure , and to prevent a heart attack, and it is one of the ace inhibitors which very often, will cause a cough.

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Drug InteractionsHypotensionPatients on Diuretic TherapyPatients on diuretics and especially those in whom diuretic therapy was recently instituted may occasionally experience an excessive reduction of blood pressure after initiation of therapy with lisinoprilThe possibility of symptomatic hypotension with lisinopril can be minimized by discontinuing the diuretic prior to initiation of treatment with lisinopril and/or lowering the initial dose of lisinoprilsee WarningsHypotension and Dosage

Patients with Impaired Liver FunctionHepatitisjaundicehepatocellular and/or cholestaticelevations of liver enzymes and/or serum bilirubin have occurred during therapy with lisinopril in patients with or without pre-existing liver abnormalitiessee Adverse EffectsIn most cases the changes were reversed on discontinuation of the drug.

LactationMilk of lactating rats contains radioactivity following administration of 4 lisinopril.

Studies in rats indicate that lisinopril crosses the blood-brain barrier poorly.

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