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Dosing should be titrated based on clinical assessments of rejection and tolerabilityLower Prograf dosages than the recommended initial dosage may be sufficient as maintenance therapyAdjunct therapy with adrenal corticosteroids is recommended early post-transplant.

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Prograf is indicated for the prophylaxis of organ rejection in patients receiving allogeneic liver transplantsIt is recommended that Prograf be used concomitantly with adrenal corticosteroidssee Clinical StudiesTherapeutic drug monitoring is recommended for all patients receiving Prografsee DOSAGE AND ADMINISTRATION

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