Lithium eskalith, lithobid ; amphotericin b amphotec, ambisome, abelcet ; methenamine hiprex, mandelamine, urex ; gout medication such as allopurinol zyloprim , colchicine colcrys , or probenecid benemid ; steroid medication prednisone and others ; a blood thinner such as warfarin coumadin, jantoven ; insulin or oral diabetes medication; laxatives; an ace inhibitor such as benazepril lotensin , enalapril vasotec , lisinopril prinivil, zestril , quinapril accupril , ramipril altace , and others; or indomethacin indocin or other nsaids non-steroidal anti-inflammatory drugs such as aspirin, ibuprofen advil, motrin , naproxen aleve, naprosyn, naprelan, treximet , celecoxib celebrex , diclofenac arthrotec, cambia, cataflam, voltaren, flector patch, pennsaid, solareze , indomethacin indocin , meloxicam mobic , and others.

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The appropriate initial dosing of Coumadin varies widely for different patientsNot all factors responsible for warfarin dose variability are knownand the initial dose is influenced by:

VKORC1 and CYP2C9 gene variants generally explain the largest proportion of known variability in warfarin dose requirements.

Instruct patients about prevention measures to minimize risk of bleeding and to report signs and symptoms of bleedingsee PATIENT INFORMATION

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a double blind clinical trial conducted at the university of pittsburgh medical center indicated that ginseng extracts may reduce the efficiency of coumadin a blood thinner 38 .