Tracey when i finally got diagnosed in march 2012 i was put on methotrexate initially 6 now 8 once a week plaquenil 1 a day i was also put on prednisone for long enough for the methotrexate to kick in.

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Many things can affect the dose of medication that a person needssuch as body weightother medical conditionsand other medicationsIf your doctor has recommended a dose different from the ones listed heredo not change the way that you are taking the medication without consulting your doctor.

Anorexianauseavomitingdiarrheaand abdominal crampsIsolated cases of abnormal liver function and fulminant hepatic failure.

If any visual disturbance occursvisual acuitycolor visionthe drug should be immediately discontinued and the patient closely observed for possible progression of the abnormalityRetinal changesand visual disturbancesmay progress even after cessation of the therapysee ADVERSE REACTIONS

Are allergic to hydroxychloroquine or any ingredients of the medication are allergic to any of the 4-aminoquinoline compoundssuch as chloroquine have been previously diagnosed with retinopathy of the eye.

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in 2002, the american academy of ophthalmology aao established ocular examination guidelines for screening patients on plaquenil therapy.